RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-140
RNA ID
MI0000165
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; ELISA etc.
Target
NA
Pathway
TGF-B1/SMAD3 signaling pathway
PubMed ID
23967091
Title
Low-dose paclitaxel ameliorates pulmonary fibrosis by suppressing TGF-B1/Smad3 pathway via miR-140 upregulation
Year
2013
Function
Low-dose PTX prevents EMT and pulmonary fibrosis by suppressing the TGF-B1/Smad3 pathway via upregulating miR-140.